Some 1.6 million Americans have opioid use disorder (OUD), and the overdose crisis has worsened over the past several years, with preliminary data from 2019 and 2020 indicating that opioid overdose death rates are climbing. FDA-approved medications—specifically, buprenorphine and methadone—have been shown to reduce the risk of overdose, illicit opioid use, and the transmission of infectious disease that can accompany injection drug use. Unfortunately, only 18% of people with OUD in the United States received any of the three FDA-approved lifesaving treatments in 2019: buprenorphine, methadone, and naltrexone.
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